Statins and Cholesterol

Statins are among the most very suggested and also commercially successful medicines in contemporary society, due to their ability to lower LDL-cholesterol as well as lower the danger of creating cardio condition. Discover more regarding the history, system, and side impacts of statins in this episode of Medicurio.

Other lipoprotein particles:
You might have listened to of LDL cholesterol as “negative” cholesterol since it clogs up the blood vessels with plaque. Its equivalent, HDL or “excellent” cholesterol does the opposite – HDL fragments move throughout the blood stream and grab any kind of cholesterol it discovers and also brings it back to the liver. Many times, plaque development is reliant on both just how much LDL as well as just how little HDL there is in the blood.

Dr. Endo’s story on his exploration of compactin: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108295/

CVD Risk Calculator by the American College of Cardiology: http://tools.acc.org/ASCVD-Risk-Estimator-Plus/

Referrals:

Hajar R. Statins: Past as well as Present. Heart Views: The Official Journal of the Gulf Heart Association. 2011; 12( 3 ):121 -127.

Thompson, P. D., Clarkson, P., Karas, R. H. (2003 ). Statin-associated myopathy. Journal of American Medical Association, 289( 13 ): 1681-1690.

Golomb, B. A., & Evans, M. A. (2008 ). Statin Adverse Effects: A Review of the Literature and also Evidence for a Mitochondrial Mechanism. American Journal of Cardiovascular Drugs: Drugs, Devices, and Other Interventions, 8( 6 ), 373– 418.